Horses from the Clarehaven yard have won the accolade three times in the last four years - Kingman (2014), Golden Horn (2015) and Enable (2017) and this time Cracksman, Enable, Roaring Lion and Stradivarius are all in the running.
Alpha Centauri collected four Group One prizes this term - the Tattersalls Irish 1,000 Guineas, the Coronation Stakes, the Tattersalls Falmouth Stakes and the Prix du Haras de Fresnay-le-Buffard Jacques le Marois - for trainer Jessica Harrington before injury ended her racing career.
The 28th Cartier Racing Awards will be presented at a ceremony at the Dorchester Hotel on Tuesday.
The nominations for each of the equine awards, in alphabetical order, are as follows:
Cartier Horse Of The Year
Alpha Centauri
Cracksman
Enable
Roaring Lion
Stradivarius
Cartier Older Horse
Cracksman
Enable
Lightning Spear
Poet's Word
Cartier Three-Year-Old Colt
Masar
Roaring Lion
Sands Of Mali
Saxon Warrior
Cartier Three-Year-Old Filly
Alpha Centauri
Laurens
Sea Of Class
Wild Illusion
Cartier Sprinter
Battaash
Mabs Cross
Merchant Navy
Sands Of Mali
Cartier Stayer
Holdthasigreen
Kew Gardens
Stradivarius
Vazirabad
Cartier Two-Year-Old Colt
Advertise
Quorto
Ten Sovereigns
Too Darn Hot
Cartier Two-Year-Old Filly
Fairyland
Hermosa
Pretty Pollyanna
Skitter Scatter
Fast Results
Scores
