Review and updated Sky Bet odds from Tuesday night's action in the Premier League.
United ultimately sealed victory with a brilliant solo goal from Jesse Lingaard four minutes from time to finally sink the Hornets' hopes.
Sky Bet's biggest winning RequestABet was Martial to score, Manchester United to win, both teams to score and Marcos Rojo to be carded at 18/1.
Mauricio Pochettino's Tottenham slipped up again as brilliant first-half goals from Jamie Vardy and Riyad Mahrez handed Leicester a 2-1 win at the King Power Stadium.
Spurs have been pushed out from 50/1 to 100/1 in Sky Bet's title odds.
Vardy latched onto a ball over the top from Marc Albrighton to volley a superb 13th minute opener, then Mahrez curled home Leicester's second on the stroke of half-time.
Already reeling from their dropped point at home to West Brom at the weekend, Spurs reduced the deficit when Harry Kane lashed home a through-ball from the returning Erik Lamela 11 minutes from time.
Spurs almost snatched a point in the final seconds when first Danny Rose had a penalty appeal turned down, then Dele Alli flashed a final shot just wide.
Newcastle hit back from two goals down to grab a 2-2 draw at West Brom and end a run of four consecutive defeats.
The home side looked set for victory through goals from Hal Robson-Kanu and Sam Field either side of half-time, but Ciaran Clark's header gave Newcastle hope on the hour mark.
That belief paid off seven minutes from time when Matt Ritchie's ball into the box took a couple of deflections and went into the net off Baggies defender Jonny Evans.
The draw went out to 16/1 in Sky Bet's in-running odds when West Brom, who were as short as 1/20 to win, went 2-0 up.
Brighton goalkeeper Matthew Ryan was the Seagulls star in an otherwise forgettable goalless draw against bottom club Crystal Palace.
Ryan pulled off a superb early save to deny Wilfred Zaha as the Eagles were once again left searching for their first away goal of the season.
Palace are 6/4 third-favourites in Sky Bet's relegation odds. That's behind Swansea's (4/11) and Huddersfield (11/8).
Brighton can be backed at 7/2 to go down.