Red Bull Salzburg scored four times in 20 minutes to stun Lazio and make it through to the Europa League semi-finals.
Marseille were another side that overturned a deficit, with a 5-2 victory over RB Leipzig enough for them to progress.
Leipzig held a slender 1-0 advantage from the initial meeting in Germany and they got a crucial away goal through Bruma just 64 seconds into the second leg.
Yet the tie was soon level as Stefan Ilsanker scored an own goal and Bouna Sarr added a second before Florian Thauvin's effort gave Marseille an aggregate lead prior to half-time.
Leipzig hit back through Jean-Kevin Augustin, and at that point they would have progressed on away goals, only for ex-West Ham winger Dimitri Payet and Hiroki Sakai to score and make sure of Marseille's progress via a 5-3 aggregate success.
- 5/6 Atletico Madrid
- 9/4 Arsenal
- 13/2 Marseille
- 7/1 Salzburg