Away from the headline clash at the Etihad, there are three other games in the Premier League on Sunday. Joe Townsend has best bets for each.
1pt Sheffield United and Leeds to draw at 49/20
1pt Heung-min Son and Harry Kane both to score for Tottenham against Newcastle at 4/1
1pt Tomas Soucek to have 2+ Total Shots for West Ham against Wolves at 21/10
For details of advised bookmakers and each-way terms, visit our transparent tipping record
Prior to football's pause button being hit last season, Sheffield United were right in contention for a top six finish during what was an incredible first campaign in the top flight following promotion from the Sky Bet Championship.
Since football returned, the Blades' form has tailed off sharply - they've won three, drawn three and lost eight matches in all competitions. Chris Wilder's side lost only eight of 33 fixtures before the pandemic.
But there are positives to cling to for Sheffield United fans despite defeat in their opening two Premier League games. After being caught cold by Wolves to trail 2-0 inside five minutes on opening weekend, Wilder's men battled hard and could quite easily have taken something from the game.
Then at Aston Villa they had John Egan sent off after just 12 minutes, missed a first-half penalty and were only beaten by a header from a corner in the final half-hour.
Ever the pragmatist, Wilder will be determined to avoid a third straight magnanimous defeat, and sixth league loss in a row.
Leeds have won plenty of plaudits for their gung-ho style under Marcelo Bielsa, which saw them come out on the wrong side of a 4-3 thriller against champions Liverpool, but edge fellow newly-promoted side Fulham by the scoreline.
Defensively though, they have been really poor. That is surely something Bielsa will be looking to address having guided Leeds to promotion by conceding the fewest goals and keeping the most clean sheets in the Championship last season.
In the Whites' opening two games they have faced similarly minded opponents, whose instinct is to attack first and defend second. That won't be the case at Bramall Lane.
Recent results mean both teams are big prices to keep a clean sheet - Sheffield United at 5/2 and Leeds at 9/4 - but neither doing so would surprise me in the least. The absence of a Carabao Cup tie in midweek will have given each manager some much-needed preparation time to iron out any issues on the training ground.
The Blades have not played badly in their two games so far, while Leeds were fortunate to race into a 4-1 lead against a Fulham team who had at the very least matched them up to that point.
With the draw the outside bet, at a juicy price of 49/20, it's difficult to ignore.
A pair of tight 1-0 away victories when the sides met during a close-run 2018/19 promotion race could be an indicator of how this contest will play out.
I'll happily acknowledge that I seem to be in the minority, but I just cannot shake the feeling that Wilder's Blades could frustrate Leeds and dig out a narrow win, which makes Sheffield United to beat Leeds - Draw No Bet at 20/21 a tempting option.
But the value is with the draw.
Score prediction: Sheffield United 1-1 Leeds (Sky Bet odds: 11/2)
Best bet: Sheffield United and Leeds to draw at 49/20
What a week it's been if you're a Tottenham fan.
It began on Saturday with the much-vaunted loan return of Gareth Bale, and the less talked about but still significant £25m signing of left-back Sergio Reguilon, also from Real Madrid.
An incredible 'we're still here' performance followed the next day as Heung-min Son scored four times at Southampton, astonishingly all assisted by Harry Kane, before the England captain found the net himself in a ruthless 5-2 win.
Then their Carabao Cup tie with Leyton Orient was called off because of a number of positive Covid-19 tests at the Sky Bet League Two club.
To round things off Spurs won their Europa League qualifier against Shkendija, a night that will be best remembered for Jose Mourinho being proved right when he claimed the North Macedonian team's goals were too small.
Oh, and there's been all of drama about Dele Alli potentially leaving too - he started on Thursday night by the way.
After all that excitement, what are the odds on Sunday's meeting with Newcastle being goalless? 14/1.... fat chance.
Steve Bruce's side were thrashed 3-0 at home by Brighton last weekend, a match they deserved to lose by more. The way they defended will have Tottenham's forwards licking their lips.
It would be remiss of me not to mention that the Magpies did respond with a stunning 7-0 win at League Two club Morecambe in the cup, but that's not going to help them keep out Son and Kane in north London.
The duo scored again on Thursday, and they're 4/1 to both be on the scoresheet for a third straight game.
They really are on fire, with Son bagging two assists in midweek as well. Both found the net at St James' Park when these sides met back in July too so have proven in recent times that they have the beating of the Newcastle defence.
While it was the South Korean who netted four times at Southampton, it's Kane who has the phenomenal record of scoring more than once in a game, doing so on eight occasions for club and country last season. It's a market to keep an eye for a price boost right up until kick-off and in-play, having paid out for us at 10/1 against Leicester during Project Restart last term.
The current 4/1 on offer is just a little too skinny, with the Kane and Son double act a smarter play having scored eight of Tottenham's 10 goals between them this season.
Score prediction: Tottenham 3-1 Newcastle (Sky Bet odds: 10/1)
Best bet: Heung-min Son and Harry Kane both to score at 4/1
Leicester were beaten in all six meetings with top-three teams last term – three of which arrived by a margin of two goals or more. They regularly flopped against the Premier League’s leading lights, taking top honours just once in 12 against top-seven finishers and the guests head to Manchester having suffered six defeats in the past seven head-to-heads.
Man City covered this line in 11 of their 19 Etihad encounters in 2019/20 – Liverpool, Arsenal and Leicester all departed with defeats by two goals or more – keeping clean sheets along the way in 10 of those home outings. They should be well capable of repeating the feat on Sunday should they pick up where they left off at half-time at Molineux.
Elsewhere, the imperious Kevin De Bruyne could be underrated in the shots on target market to land two or more should Guardiola continue to ask the Belgian to play a more advanced role. The PFA Players' Player of the Year is on penalty and set-piece duty and all four of his strikes at goal against Wolves were on target, suggesting 5/4 could be overpriced.
Last season, De Bruyne averaged over three shots per-game and also hit five on target during his side's disappointing Champions League exit against Lyon. With Leicester giving up too many chances to a bare-boned Burnley only seven days ago, KDB is likely to be given enough opportunities in front of goal to make a mark.
Prediction: Manchester City 3-1 Leicester (Sky Bet odds: 17/2)
Best Bets:
A home defeat by Newcastle on opening day added to the growing discontent at London Stadium over a lack of transfer activity, but West Ham showed encouraging signs against Arsenal last weekend - a game which they probably deserved to win.
David Moyes' side were well-organised defensively and threatening on the counter attack, but a late goal cost them dear.
They have sandwiched that unlucky loss with emphatic wins over Sky Bet League One opposition in the Carabao Cup, so confidence shouldn't be a huge issue. There will be a strange feeling in the dressing room though, with Alan Irvine taking charge as Moyes, along with players Issa Diop and Josh Cullen, self-isolates following a positive coronavirus test.
As has been the case for a while now, West Ham's shining light against Arsenal was Michail Antonio.
A raging bull, the Gunners defence struggled to contain him. He drew the Hammers level on half-time by scrappily finishing a superb break, before heading against the bar and later failing to properly connect from close-range, allowing Bernd Leno to make an easy save.
Since lockdown no player has been more prolific in the Premier League, with the West Ham forward's nine goals putting him on a par with Danny Ings and Raheem Sterling.
And yet Antonio is 11/4 to score on Saturday - more tempting than the 13/8 on offer for Raul Jimenez, although the Wolves striker has scored in both their league matches this season.
What doesn't go in our favour is Wolves' tendency to be involved in low-scoring encounters. Their 3-1 home defeat by Manchester City on Monday was only the second time in 15 fixtures that a game of theirs has seen over 2.5 goals.
I hope at least someone took heed of my tip-off in this week's Premier League: Pointing Pointers as the price of 13/11 on under 2.5 goals is long gone. Given last weekend's utter mayhem, I wouldn't risk it now at 11/14. The value just isn't there.
I still expect this to be tight, and so prefer a shots, rather than anytime goalscorer, angle. It might surprise you to know that for all the criticism that's been sent the Irons way, they've had 29 shots in the Premier League already this season.
Tomas Soucek is 9/2 for 2+ Shots On Target and 21/10 for 2+ Total Shots. The midfielder has managed two and three shots respectively so far this season, and is always a threat at set-pieces. Last weekend he was unlucky not to win a penalty when his header was blocked by the arm of Arsenal defender Gabriel.
I'm taking the shorter price for him to be in the thick of it once again.
For a more speculative bet, but grounded in very recent evidence, Wolves defender Romain Saiss had three attempts, scoring with one, away at Sheffield United on opening weekend. He is 5/1 for 2+ Total Shots and 22/1 for three.
Stranger things and all that.
Score prediction: West Ham 1-1 Wolves (Sky Bet odds: 5/1)
Best bet: Tomas Soucek to have 2+ Total Shots at 21/10
Odds correct at 1200 BST 25/09/20
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