Liverpool play their game in hand on Wednesday, travelling to West Ham looking to extend their lead at the top to 19 points. George Pitts looks at the betting.
1pt Alex Oxlade-Chamberlain to score anytime at 3/1
For details of advised bookmakers and each-way terms, visit our transparent tipping record
West Ham are without a win in their last four in all competitions and, with a number of injury concerns, David Moyes could really do with a few bodies adding to his squad before Friday's transfer window deadline.
They were poor against Sky Bet Championship leaders West Brom, managed by former boss Slaven Bilic, on Saturday in the FA Cup and the last thing they need is the visit of unbeaten Liverpool, flying high at the top of the table.
The Reds' 40-game unbeaten streak in the Premier League has been incredible and, of all teams to end it, West Ham would not be on the list - although it is the first time they will have met this season. Can they be their Kryptonite? Probably not but they can try.
After pretty much six days' rest for Liverpool due to the heavy rotation in the FA Cup at the weekend, which led to that criticism of Jurgen Klopp following his comments about the replay, they should be pretty refreshed.
Klopp may be taking the stick at the minute but, come May, he will not mind when he inevitably has a Premier League winner's medal around his neck.
Without Sadio Mane due to a short term injury, the German will have to make a change on the left and it looks likely to be either Divock Origi or Alex Oxlade-Chamberlain with January signing Takumi Minamino still being gradually introduced to English football.
Oxlade-Chamberlain may well be given the nod in a further advanced role over Origi and it could be worth taking the 3/1 anytime price available on him before it shortens.
He has had a decent run in the side of late and he is not afraid of trying his luck, averaging two shots per game in Europe and 1.5 per game in the Premier League.
In three of their last five games he has had two shots on goal and in the game before that, against Brighton, he registered four efforts in just under 80 minutes.
The 26-year-old has six goals in all this season but he is without one in his last eight Reds appearances, so he would be the first to admit he is due one.
In that advanced role at the London Stadium, against a Hammers defence featuring an ageing Pablo Zabaleta, he has a great chance of finding the back of the net.
Elsewhere, the win-to-nil could be on at 11/8. Their defence has improved after a rocky start, with the return of Alisson Becker in goal making them even stronger and they have had a clean sheet in seven of their last eight. Tempting, but we will stick with the Ox.
Prediction: West Ham 0-2 Liverpool (Sky Bet odds: 6/1)
Best bet: Alex Oxlade-Chamberlain to score anytime at 3/1
Free Carabao Cup semi-final tips, prediction and best bets for the Manchester derby second leg, as Pep Guardiola's side hold the advantage. Take a read by clicking the image below...
Odds correct as of 1840 GMT on 28/01/20
We are committed in our support of responsible gambling. Recommended bets are advised to over-18s and we strongly encourage readers to wager only what they can afford to lose.Sky Bet's responsible gambling tools are detailed here and if you are concerned about your gambling, please call the National Gambling Helpline on 0808 8020 133, or visit begambleaware.org.