The ninth European Tour event of 2019, and the PDC's first ever tournament staged in the Czech Republic, saw 32 players in action on the opening day at the PVA Expo.
Rising Australian star Cadby, who was starring in a European Tour event for the first time since returning to the PDC ProTour earlier this year, got off to a perfect start on the big stage with a 6-0 demolition of Wessel Nijman.
"I've been the underdog for a while but I'm thankful to be playing here in front of this amazing crowd," said Cadby, who will face Michael Smith in Saturday's second round.
"I can't wait to get back out here tomorrow against Michael. I've beaten him on the two occasions we've met previously and I'm ready for a third."
Friday's first round of the £140,000 tournament saw 32 qualifiers competing, 11 of whom harboured hopes of forcing their way into qualifying positions for the Betfred World Matchplay ahead of Sunday's qualification cut-off.
Keegan Brown took a huge step towards a third Winter Gardens appearance with a 6-0 whitewash of Czech Qualifier Ondrej Plsek; a result which ended Kyle Anderson's hopes of making it to Blackpool.
World Cup finalist William O'Connor must reach the quarter-finals if he is to snatch a World Matchplay place, and he too got off to the best possible start with a 6-0 success over another Host Nation Qualifier Vaclav Shieferdecker.
Dutchman Ron Meulenkamp is tasked with reaching the semi-finals and he also kept his hopes alive with a 6-2 success over Czech debutant Jan Hlavacek.
Jamie Hughes, Ted Evetts and Justin Pipe are all required to land the £25,000 top prize if they are to qualify for the biggest even of the summer and the trio recorded victories over Devon Petersen, Krzysztof Ratajski and Madars Razma respectively.
World Cup star Karel Sedlacek was the sole Czech representative to make it through to round two with a gripping 6-5 success over Brendan Dolan, ending the Northern Irishman's World Matchplay hopes in the process.
Robert Thornton, Rowby-John Rodriguez and Razma were the other three players to see their feint Blackpool hopes extinguished with defeats at the hands of Stephen Bunting, Andrew Gilding and Pipe respectively.
A winner of two ProTour titles in his debut PDC campaign, Glen Durrant is already assured of his World Matchplay debut and he produced an outstanding 110.12 average in his 6-1 win over Daniel Larsson to set up a meeting with Gerwyn Price.
Elsewhere, Danish Darts Open finalist Chris Dobey got his campaign off to a 6-2 winning start over Poland's Sebastian Steyer, while Dutch pair Jermaine Wattimena and Danny Noppert were victorious over Kevin Garcia and Stefan Bellmont.
Saturday's second day of the Czech Darts Open will be broadcast on video.pdc.tv, and through a series of bookmakers' websites.
Schedule of play
Friday June 28
First Round (Best of 11 legs)
Afternoon Session (1200 BST)
- Danny Noppert 6-2 Stefan Bellmont
- Madars Razma 4-6 Justin Pipe
- Jermaine Wattimena 6-0 Kevin Garcia
- Karel Sedlacek 6-5 Brendan Dolan
- Wessel Nijman 0-6 Corey Cadby
- William Borland 3-6 John Henderson
- Ondrej Plsek 0-6 Keegan Brown
- Andrew Gilding 6-3 Rowby-John Rodriguez
Evening Session (1815 BST)
- Glen Durrant 6-1 Daniel Larsson
- Mervyn King 6-5 Steve West
- Vaclav Shieferdecker 0-6 William O'Connor
- Krzysztof Ratajski 3-6 Ted Evetts
- Chris Dobey 6-2 Sebastian Steyer
- Ron Meulenkamp 6-2 Jan Hlavacek
- Stephen Bunting 6-3 Robert Thornton
- Jamie Hughes 6-4 Devon Petersen
Saturday June 29
Second Round (Best of 11 legs)
Afternoon Session (1200 BST)
- Jonny Clayton (13) v Jermaine Wattimena
- Darren Webster (16) v Danny Noppert
- Simon Whitlock (14) v Justin Pipe
- Nathan Aspinall (15) v Andrew Gilding
- Daryl Gurney (4) v William O'Connor
- Ian White (2) v Karel Sedlacek
- Steve Beaton (10) v Ron Meulenkamp
- James Wade (6) v Mervyn King
Evening Session (1815 BST)
- Ricky Evans (9) v Ted Evetts
- Joe Cullen (12) v Chris Dobey
- Peter Wright (5) v Stephen Bunting
- Michael van Gerwen (1) v Keegan Brown
- Mensur Suljovic (8) v John Henderson
- Gerwyn Price (3) v Glen Durrant
- Adrian Lewis (7) v Jamie Hughes
- Michael Smith (11) v Corey Cadby
Sunday June 30
Afternoon Session (1200 BST)
Third Round (Best of 11 legs)
- Eight matches
Evening Session (1815 BST)
Quarter-finals (Best of 11 legs)
- Four Matches
Semi-finals (Best of 13 legs)
- Two Matches
Final (Best of 15 legs)
- Winner SF 1 v Winner SF 3